Evidence-Based Knowledge

Fertility Facts You Should Know

How long can frozen sperm, eggs, and embryos last? What are real IVF success rates? Get the numbers that matter for your family-building journey.

28+

Years

Longest successful pregnancy from frozen sperm

31

Years

Oldest frozen embryo to result in a live birth

95%

Survival Rate

Eggs frozen before 36 surviving thaw

69%

IVF Success

Live birth rate per transfer under age 35

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🧊

Frozen Sperm

How long does it really last?

Indefinitely

No confirmed expiration date

Sperm frozen at -196°C in liquid nitrogen can remain viable indefinitely. Successful pregnancies have been recorded from sperm stored for over 28 years.

Zero

Quality loss from storage time

A study of 119,558 samples over 15 years found storage duration had no significant effect on motility, fertilization rates, or live birth rates.

FDA Quarantine Requirement

Donor sperm must be quarantined for at least 6 months and the donor retested for infectious diseases before the sample can be released for use. This applies to all anonymous donations in the United States.

Source: FDA regulations, ASRM guidelines

7–14 Days

Shipping window in dry shippers

Frozen sperm is routinely shipped nationally and internationally in dry shippers — portable liquid nitrogen tanks that maintain -150°C to -196°C without power for 7–14 days. Major carriers like FedEx and UPS handle these shipments daily. Most sperm banks offer direct-to-clinic or direct-to-home delivery. International transport may require customs paperwork and import permits depending on the destination country.

🥚

Frozen Eggs

Vitrification changed everything

95%+

Survival rate after thaw (under 36)

Eggs frozen from women under 36 using vitrification (flash-freezing) have a survival rate exceeding 95%. Quality at time of freezing is what matters most.

1 in 4

Eggs become a healthy embryo

For women under 35, roughly 1 in 4 frozen eggs becomes a genetically healthy embryo, with a fertilization rate around 77%.

<80%

Survival rate over 40

Egg survival rates drop below 80% for women over 40 at time of freezing, with very few eggs yielding chromosomally normal embryos.

No longer experimental

As of 2021, ASRM declared oocyte cryopreservation a standard of care for fertility preservation — no longer an experimental procedure.

Source: ASRM Practice Committee, 2021

🧬

Frozen Embryos

The longest shelf life in fertility

31 Years

Longest successful freeze

A healthy baby was born from an embryo frozen in 1994 and transferred in 2025 — 31 years in storage.

95-99%

Blastocyst thaw survival

With modern vitrification, 95-99% of day-5 blastocysts survive thawing. Storage duration does not significantly impact viability.

Frozen = Fresh (or better)

Pregnancy rates from frozen embryo transfers are now equal to or better than fresh transfers for most patients. Many clinics now prefer freeze-all protocols.

Source: SART national data

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IVF Success Rates by Age

Live birth rate per embryo transfer (SART data)

69%

Under 35

58%

35–37

43%

38–40

24%

41–42

7%

Over 42

With PGT-tested embryos: Live birth rates improve to 70–80% per transfer regardless of maternal age at embryo creation. Freezing 15–20 eggs before age 35 gives roughly an 80% cumulative live birth rate.

Source: SART (Society for Assisted Reproductive Technology) national data

💬

Sperm Donor Facts

What the screening process really looks like

1–5%

Acceptance rate

Only 1–5% of sperm donor applicants pass all screening rounds at major sperm banks. The process includes physical exams, genetic testing, psychological evaluations, and semen analysis.

18–39

Required age range

Most sperm banks require donors to be 18–39 years old. ASRM recommends donors ideally be under 40 to minimize risks associated with advancing paternal age.

Mandatory FDA Screening

Every donor is tested for HIV-1 & HIV-2, Hepatitis B & C, syphilis, HTLV-1 & 2, and CMV within 7 days of each donation. Expanded carrier screening covers 100+ genetic conditions.

Birth limits

ASRM recommends no more than 25 live births per donor per 800,000 population to prevent half-siblings from unknowingly meeting. The FDA does not set a legal cap.

Source: ASRM gamete donation guidance, 2024

🌸

Egg Donor Facts

Requirements, limits, and compensation

21–34

ASRM recommended age

Donors under 21 require additional psychological evaluation. For donors over 34, cytogenetic risks must be disclosed to intended parents.

6 Max

Lifetime retrieval cycles

ASRM recommends limiting a single egg donor to no more than 6 retrieval cycles in their lifetime to protect donor health.

$8K–$30K+

Compensation per cycle

ASRM considers $5,000–$10,000 an ethical range. Market rates at private agencies commonly reach $8,000–$30,000+ depending on donor profile and location.

Source: ASRM Ethics Committee, 2021

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Surrogacy Facts

Types, success rates, and costs

Gestational Surrogacy

The surrogate has no genetic connection to the child. She carries an embryo created from the intended parents' or donor eggs/sperm. Accounts for 80–90% of all surrogacy in the U.S.

$100K–$220K+

All-in cost (U.S.)

Traditional Surrogacy

The surrogate uses her own eggs and is the genetic mother. Far less common due to greater legal and emotional complexity.

$40K–$90K

All-in cost (U.S.)

Success Rates

45–55%

Per transfer

70–80%

With PGT embryos

70–80%

Within 3 transfers

Source: Industry data, Illume Fertility cost breakdowns

⏱

Fertility Decline by Age

What the science says for women and men

Female Fertility

Egg Reserve Over Time

Women are born with all the eggs they'll ever have. By age 30, only about 12% of peak egg reserve remains. By 40, only ~3% remains.

The Decline Timeline

Fertility begins declining gradually after 32, accelerates noticeably at 37, and drops steeply after 40.

Chromosomally Normal Eggs by Age

76%

25–30

52%

35–37

40-50%

38–40

<30%

Over 40

Male Fertility

Testosterone Decline

Testosterone declines approximately 1–2% per year starting around age 30. Free testosterone drops ~1.3% per year between ages 40–70.

Sperm Quality

Sperm count declines up to 2.6% per year after age 40. Motility worsens by 3–37%. Morphology can decline ~0.9% per year.

Peak & Decline

Male fertility peaks at approximately ages 30–35. Decline accelerates from 35 and more steeply from 40. Fathers over 40 have increased risk of certain genetic conditions in offspring, including autism spectrum disorder and achondroplasia.

Source: ASRM committee opinion on advancing paternal age; meta-analysis of 90 studies (93,839 men)

❄️

Fertility Preservation

When to freeze and why

Optimal Age to Freeze Eggs

ASRM reports the highest live birth rates from eggs retrieved at ages 25–30. Clinical consensus puts the practical ideal window at 30–34.

52%

Live birth rate (frozen <35)

19%

Live birth rate (frozen 40+)

How Many Eggs to Bank

Banking 15–20 mature eggs before age 38 gives a cumulative live birth rate exceeding 70% when those eggs are used.

Why people freeze: Cancer treatment (chemo/radiation), endometriosis, career planning, not having found the right partner, or financial readiness.

Source: ASRM 2026 updated guidance; single-centre cohort of 731 women

👪

Co-Parenting & Single Parents by Choice

A rapidly growing movement

23M+

Children in single-parent homes (U.S.)

Over 23 million children in the U.S. live in single-parent families — approximately 34–35% of all children.

1.5M

Single mothers by choice (U.S.)

Approximately 1.5 million women in the U.S. are raising children alone by deliberate choice — the fastest-growing segment of single mothers.

+109%

Donor insemination growth

Single people using donor insemination increased 109% between 2011–2021. Women using IVF with donor sperm increased 178% in the same period.

34%

Joint custody rate

Joint custody was used in only 13% of families before 1985. By the early 2010s, it rose to 34% — reflecting the growth of intentional co-parenting arrangements.

Sources: U.S. Census Bureau, Pew Research, Single Mothers by Choice

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Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Statistics are sourced from ASRM, SART, FDA, and peer-reviewed research as cited. Individual outcomes vary significantly. Always consult a qualified fertility specialist or reproductive endocrinologist for advice specific to your situation.